Oroxcell

Human in vitro models for chemicals and cosmetics safety evaluation

In vitro safety assessement of raw ingredients and cosmetics products. These in vitro tests are in accordance with REACH and 7th Amendment to the EU Cosmetics Directive recommandations on the use of alternative to animal testing methods. Some of these tests have been validated by ECVAM and OECD.

1. Reconstructed human epidermis

Models of reconstructed human epidermis distributed by SkinEthic, Episkin and RHE to assess :

• Skin corrosion of chemicals
• Skin Irritation assay of chemical and cosmetics
• Permeability and metabolism prediction

2. Human Corneal Epithelium

HCE model by SkinEthic for :

• Ocular irritation assay

More on cellular toxicity testing (PDF)